CTEPH symptoms are nonspecific1:
Indistinguishable from symptoms of other forms of pulmonary hypertension (PH)
Can be mistaken for respiratory diseases, including asthma and chronic obstructive pulmonary disease (COPD)
On physical examination, initial findings consistent with CTEPH may include1:
A reduction in the splitting of the second heart sound (S2)
Accentuation of the sound of pulmonic closure (P2)
A palpable right ventricular heave
Subsequent findings correspond to decreasing right ventricular function1:
Jugular venous distention
Fixed splitting of S2
Right-sided third heart sound (S3)
Tricuspid regurgitation
Hepatomegaly, ascites, and peripheral edema
Reference:
1. Piazza G and Goldhaber SZ. Chronic thromboembolic pulmonary hypertension. N Engl J Med. 2011;364:351-360..