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Patients with Inoperable CTEPH

In a 2011 registry of 679 CTEPH patients, 37% (247) were deemed inoperable1

According to the Fifth World Symposium on Pulmonary Hypertension that convened in 20132:

  • All patients diagnosed with CTEPH should receive lifelong anticoagulation

  • Comparing radiographic burden of disease with hemodynamics is critical to determining operability and risk from surgery before performing pulmonary thromboendarterectomy (PTE) (also called pulmonary endarterectomy [PEA])

  • Overall operability assessment must consider patient factors, including comorbidities


Operability assessment remains a subjective process, so reevaluation of operability by a second experienced CTEPH center in cases initially deemed inoperable is recommended.2

noperable CTEPH patients table

PTE myth

Watch to find out if very ill patients can be considered for PTE


1. Pepke-Zaba J, Delcroix M, Lang I, et al. Chronic thromboembolic pulmonary hypertension (CTEPH): results from an international prospective registry. Circulation. 2011;124(18):1973-1981. 2. Kim NH, Delcroix M, Jenkins DP, et al. Chronic thromboembolic pulmonary hypertension. J Am Coll Cardiol. 2013;62(suppl D):D92-D99.